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IL-4、IFN- γ、 SiGe had no correlation with FEV1 (P & gt; 0.05), IL-4 and IFN- γ、 SiGe had no correlation with PEF (P & gt; 0.05), IL-4 and IFN- γ There was no correlation with FEV1 / FVC (P & gt; 0.05), and SiGe was positively correlated with FEV1 / FVC (P & lt; 0.05).

The rats in the experimental group wore self-made leading device all day, and the rats in the control group did not wear appliance.

Increased expression of IL-4 and IFN- γ The decrease of expression leads to the occurrence and development of inflammatory process of asthma### Objective to investigate the effect of mandibular lead on the content of bone morphogenetic protein-2 (BMP-2) in rat condylar chondrocytes.

Results the level of plasma IL-4 in asthma group was significantly higher than that in control group- γ The level of plasma SiGe was lower than that in the control group, and the level of plasma SiGe was higher than that in the control group (P & lt; 0.05).

ERK1 / 2 in esophageal cancer may participate in the EMT process, thus promoting the invasion and metastasis of esophageal cancer cells### Objective to study the plasma interleukin-4 (IL-4) and γ- Interferon (IFN)- γ)、 The role of specific IgE (SiGe) in the pathogenesis of childhood asthma and its correlation with pulmonary function.

SiGe can provide reference for whether bronchial asthma is in acute attack.

Conclusion the expression of plasma IL-4 is increased and plasma IFN is increased in children with asthma- γ Decreased expression.

Methods plasma IL-4 and IFN were detected by biotin double antibody sandwich enzyme-linked immunosorbent assay (ELISA) in 90 children with acute attack of asthma (asthma group) and 90 healthy children of the same age and sex (control group)- γ、 The expression level of SiGe, pulmonary function, 1-second forced expiratory volume (FEV1), 1-second rate (FEV1 / FVC) and daily variation rate of maximum expiratory flow (PEF) in 40 children with asthma were measured, and the correlation was analyzed.

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Methods 64 male SD rats were randomly divided into experimental group and control group.

On days 0, 1, 3, 5 and 1 and 2.