Objective to investigate the serum vitamin D nutritional status of middle-aged and elderly people in Beijing and to explore the correlation between 25 hydroxyvitamin d [25 (OH) D] and dyslipidemia.
Methods a cross-sectional survey was conducted on 448 middle-aged and elderly people in a community in Beijing.
Objective to determine the risk factors of neurological complications (NC) in left heart infective endocarditis (ie) and its impact on cardiac surgery and prognosis.
According to the quartile of 25 (OH) d, the prevalence of dyslipidemia increased with the decrease of 25 (OH) d level; TC, TG and LDL-C increased and HDL-C decreased; After adjusting for age, gender and other factors, logistic regression showed that the risk of dyslipidemia in the lowest quartile of 25 (OH) d was 143% higher than that in the highest quartile..
During the follow-up period (median time 17 months), 70 cases (22.7%) died.
Conclusion NC is associated with poor prognosis of ie.
For IE patients with NC, valve surgery is relatively safe and may improve the prognosis of specific patients.
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Results among the 448 subjects, 234 were dyslipidemia, accounting for 52.23% of the total population.
Clinical trial registration China clinical trial registration center, chictr-trc-10001618.
Objective to investigate the effect of short-term intensive insulin therapy on plasma lipoprotein associated phospholipase A2 (LP 2) and secretory phospholipase A2 (sPLA2) level in newly diagnosed type 2 diabetes mellitus (T2DM) patients and its clinical significance.
NC was independently associated with poor long-term prognosis (HR = 2.292, 95% CI 1.274 ~ 4.122, P = 0.006).
Results a total of 308 patients, aged (45.3 ± 15.9) years, developed NC in 65 cases (21.1%).
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The hospitalization and 1-year IE related mortality of patients undergoing valve surgery in NC group were also significantly lower (14.8% vs 5.3%, 18.5% vs 73.7%, P & lt; 0.001, respectively).
90 patients with newly diagnosed T2DM received continuous subcutaneous insulin infusion (CSII) with insulin pump for 2 weeks.
A 32 year old patient with severe acute pancreatitis induced by hypertriglyceridemia in the third trimester of pregnancy caused multiple organ failure, pancreatic necrosis and infection, abdominal compartment syndrome and intrauterine fetal death.
Methods the clinical data, NC, treatment and prognosis of patients with left heart ie admitted and diagnosed from 2001 to 2012 were analyzed.
Peking University core and science and technology core papers were published, and SCI was published.
The level of 25 (OH) d in the dyslipidemia group was significantly lower than that in the normal blood lipid group, P mean & lt; 0.05。 The 25 (OH) d level of our group is 15.7 (12.2, 20.1) μ G / L, of which 91.1% were vitamin D deficiency.
The general data, biochemistry, blood lipid and 25 (OH) d were collected.
The levels of 25 (OH) d were compared between the two groups; The blood lipid levels of each group were compared according to 25 (OH) d quartile; Logistic regression was used to analyze the risk factors of dyslipidemia.
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156 cases (50.6%) underwent valve surgery, which significantly reduced IE related death at 1 year (HR = 0.160,95% CI 0.063 ~ 0.405, P & lt; 0.001).
Through the multidisciplinary cooperation of 10 specialties, including emergency, critical medicine, digestion, obstetrics, endocrinology, ultrasound, radiation, infection, nutrition and surgery, the patient finally improved.
Macrophyte (HR = 1.681, 95% CI 1.013 ~ 2.788, P = 0.044), non nervous system embolism (HR = 1.820, 95% CI 1.068 ~ 3.100, P = 0.028), mitral valve involvement (HR = 1.888, 95% CI 1.089 ~ 3.274, P = 0.024) Staphylococcus aureus infection (HR = 2.054, 95% CI 1.097 ~ 3.846, P = 0.024) and uncontrolled infection (HR = 4.680, 95% CI 2.563 ~ 8.546, P & lt; 0.001) were independent risk factors for NC.
The changes of plasma levels of plasma PRP 2 and sPLA2 in newly diagnosed T2DM patients after CSII treatment may be related to the improvement of insulin resistance and may play a protective role in diabetic macroangiopathy.
After treatment, sPLA2 was significantly lower than that before treatment [173.78 (80.95278.09) μ G / L ratio 219.33 (130.03337.30) μ g/L，P< 0.01], but the level of Lp-PLA2 decreased not significantly [88.35 (76.74125.18) μ G / L ratio 102.9 (76.34134.31) μ g/L，P> 0.05], but the changes of their levels before and after treatment were positively correlated with the changes of insulin resistance (HOMA-IR) evaluated by steady-state model (R values were 0.537 and 0.493, P & lt; 0.05, respectively).
macrophytes, non nervous system embolism, mitral valve involvement, Staphylococcus aureus infection and uncontrolled infection are independent risk factors of NC.
