Publication of journals (provincial journals, national journals, core journals of Peking University, SCI journals, etc.), topics, patents, monographs, scientific research projects.
The activity of superoxide dismutase (SOD) decreased significantly in medium and high dose groups (P & lt; 0.05); The content of malondialdehyde (MDA) in the high dose group increased significantly 28 days after exposure (P & lt; 0.05); The activity of superoxide dismutase (SOD) decreased significantly in high dose group (P & lt; 0.05); Catalase in each dose group.
Nano alumina suspension was prepared and administered by single tracheal drip at the doses of 14, 70 and 350 mg / kg, respectively.
(3) Compared with normal saline group, the content of malondialdehyde (MDA) in medium and high dose groups increased significantly 3 days after exposure (P & lt; 0.05).
28 days after exposure, the proportion of neutrophils in the high-dose group was still higher than that in the normal saline group, and the difference was statistically significant (P & lt; 0.05).
Our advantages: direct connection with social leaders, stable employment, ten-year reputation brand (P & lt; 0.05).
The biochemical indexes, leukocyte count classification and oxidative stress indexes were detected, and the pathological changes of the lung were observed.
Results (1) three days after exposure, the content of total protein (TP) in BALF in medium and high dose groups increased significantly (P & lt; 0.05).
The lung lavage fluid (BALF) and lung tissue were taken at 3 and 28 days after exposure.
Methods 48 male Wistar rats were randomly divided into four groups: low, medium and high dose nano alumina suspension group and normal saline group, with 12 rats in each group.
(2) Three days after exposure, the proportion of neutrophils in medium and high dose groups increased significantly compared with normal saline group (P & lt; 0.05).
Conclusion cpg-16 and cpg-17 sites of TIMP3 gene may be the key sites for the detection of promoter methylation in thyroid papillary carcinoma, and may become molecular markers for the early diagnosis of thyroid carcinoma### Objective to investigate the acute inflammatory response and oxidative stress injury of nano alumina particles on the lungs of Wistar rats.
The activities of lactate dehydrogenase (LDH), alkaline phosphatase (AKP) and acid phosphatase (ACP) in each dose group were significantly higher than those in normal saline group (P & lt; 0.05); 28d after exposure, the activity of alkaline phosphatase (AKP) in BALF in medium and high dose groups was significantly higher than that in normal saline group (P & lt; 0.05); The total protein (TP) content, lactate dehydrogenase (LDH) activity and acid phosphatase (ACP) activity in each exposed group were significantly higher than those in normal saline group (P & lt; 0.05).
